Analytical Method Development and Validation By UV and HPLC Techniques. UV, HPLC, Dissolution Methods / Hajera Khan

Public ISBD Titre : Analytical Method Development and Validation By UV and HPLC Techniques. UV, HPLC, Dissolution Methods Type de document : texte imprimé Auteurs : Hajera Khan, Auteur ; Shahed Mirza, Auteur ; Faria khan, Auteur Editeur : LAP Lambert Academic Publishing Année de publication : 2012 ISBN/ISSN/EAN : 978-3-659-24797-2 Langues : Français (fre) Catégories : Pharmacologie Résumé : Gemifloxacin,a flouroquinoline derivative has antibacterial activity. Ambroxol dibromoaminobenzyl derivatives have mucolytic activity.GEM and AMB are available in tablet dosage form (G-cin A,Lupin)for mucolytic action. The present work dealt with simultaneous estimation of GEM and AMB from bulk and tablet formulation by different UV spectrophotometric, RPHPLC and Dissolution techniques. Five UV methods were developed which are accurate, precise, rapid and economical for the estimation of GEM and AMB in Tablet dosage form. The developed HPLC method was validated in terms of accuracy, repeatability, and precision. A good linear relationship was observed for GEM An attempt has been made to carry out the dissolution study of the marketed formulation by applying four established UV-Visible Spectrophotometric methods for estimation of % release of the drug (GEM & AMB). Analytical Method Development and Validation By UV and HPLC Techniques. UV, HPLC, Dissolution Methods [texte imprimé] / Hajera Khan, Auteur ; Shahed Mirza, Auteur ; Faria khan, Auteur . - [S.l.] : LAP Lambert Academic Publishing, 2012. ISBN : 978-3-659-24797-2 Langues : Français (fre) Catégories : Pharmacologie Résumé : Gemifloxacin,a flouroquinoline derivative has antibacterial activity. Ambroxol dibromoaminobenzyl derivatives have mucolytic activity.GEM and AMB are available in tablet dosage form (G-cin A,Lupin)for mucolytic action. The present work dealt with simultaneous estimation of GEM and AMB from bulk and tablet formulation by different UV spectrophotometric, RPHPLC and Dissolution techniques. Five UV methods were developed which are accurate, precise, rapid and economical for the estimation of GEM and AMB in Tablet dosage form. The developed HPLC method was validated in terms of accuracy, repeatability, and precision. A good linear relationship was observed for GEM An attempt has been made to carry out the dissolution study of the marketed formulation by applying four established UV-Visible Spectrophotometric methods for estimation of % release of the drug (GEM & AMB).

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Code-barres	Cote	Support	Localisation	Section	Disponibilité
6368	Pharmaco 15	Livre	Bibliothèque	Pharmacologie	Exclu du prêt

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