Easy Ways to Understand HPLC, UV and Method Validation Parameters / Mazharul Islam Chowdhury

Public ISBD Titre : Easy Ways to Understand HPLC, UV and Method Validation Parameters Type de document : texte imprimé Auteurs : Mazharul Islam Chowdhury, Auteur Editeur : LAP Lambert Academic Publishing Année de publication : 2013 ISBN/ISSN/EAN : 978-3-659-40239-5 Langues : Français (fre) Catégories : Biochimie Résumé : High-pressure liquid chromatography (HPLC) used in the analytical development to quantify the biological sample concentration, the active pharmaceutical ingredient (API) and to evaluate the impurity and degradation product profiles of the drug substances (DS) and drug products (DP). Additional uses of HPLC include determination of content uniformity of dosage form, monitoring of dissolution profiles, determination of antioxidants and preservative content and supporting of cleaning validations. UV spectroscopy is one of the most frequent used techniques in pharmaceutical analysis. It involves the measurement of UV radiation absorbed by a substance in solution. The wavelength range of UV radiation is 200-400nm (180-380 nm) and the UV radiation has a sufficient energy to excite valance electrons in many atoms or molecules; consequently, UV is involved with electronic excitation. Easy Ways to Understand HPLC, UV and Method Validation Parameters [texte imprimé] / Mazharul Islam Chowdhury, Auteur . - [S.l.] : LAP Lambert Academic Publishing, 2013. ISBN : 978-3-659-40239-5 Langues : Français (fre) Catégories : Biochimie Résumé : High-pressure liquid chromatography (HPLC) used in the analytical development to quantify the biological sample concentration, the active pharmaceutical ingredient (API) and to evaluate the impurity and degradation product profiles of the drug substances (DS) and drug products (DP). Additional uses of HPLC include determination of content uniformity of dosage form, monitoring of dissolution profiles, determination of antioxidants and preservative content and supporting of cleaning validations. UV spectroscopy is one of the most frequent used techniques in pharmaceutical analysis. It involves the measurement of UV radiation absorbed by a substance in solution. The wavelength range of UV radiation is 200-400nm (180-380 nm) and the UV radiation has a sufficient energy to excite valance electrons in many atoms or molecules; consequently, UV is involved with electronic excitation.

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Code-barres	Cote	Support	Localisation	Section	Disponibilité
6362	Bioch 50	Livre	Bibliothèque	Biochimie	Exclu du prêt

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